Research Update on Links Between Parkinson’s and Circadian Rhythm Disruption

Jun 14, 2018


Parkin
and Pink1 are well-studied Parkinson’s-related genes, both broadly expressed in the brain. When they don’t function as they should, specific points of excessive contact among brain cells seem evident, the study reported, including among mitochondria — tiny cell structures that produce energy, working as the cell’s power plant.

Patients with mutations in either parkin or pink1 are known to have disturbed circadian rhythms and sleep patterns.

 

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